Kim, G.; Yoon, J-S.; Jarhad, D.B.; Shin, Y.S.; Majik, M.S.; Mulamoottil, V.A.; Qu, X.H.S.; Park, J.; Baik, M-H.; Jeong, L.S.
(Organic Letters. 19; 2017; 5732-5735.)
(?)-6'-Beta-Fluoro-aristeromycin (2), a potent inhibitor of S-adenosylhomocysteine (AdoHcy) hydrolase, has been synthesized via stereoselective electrophilic fluorination followed by a purine base build-up approach. ...