Convenient and efficient syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal

Kurangi, R.F.; Tilve, S.G.; Blair, I.A.

dc.contributor.author	Kurangi, R.F.
dc.contributor.author	Tilve, S.G.
dc.contributor.author	Blair, I.A.
dc.date.accessioned	2015-06-03T09:00:03Z
dc.date.available	2015-06-03T09:00:03Z
dc.date.issued	2006
dc.identifier.citation	Lipids. 41(9); 2006; 877-880.	en_US
dc.identifier.uri	http://dx.doi.org/10.1007/s11745-006-5043-4
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/1848
dc.description.abstract	Lipid peroxidation products 4-hydroxy-2(E)-nonenal (HNE) and 4-oxo-2(E)-nonenal (ONE) were conveniently synthesized using Wittig and Horner-Wardsworth-Emmons (HWE) reaction. Wittig or HWE reaction between an easily prepared phosphorane or phosphonate with glyoxal dimethyl acetal gave a protected 4-oxo-2(E)-nonenal. Hydrolysis gave 4-oxo-2(E)-nonenal, whereas reduction followed by hydrolysis gave 4-hydroxy-2(E)-nonenal.	en_US
dc.publisher	Springer Verlag (Germany)	en_US
dc.subject	Chemistry	en_US
dc.title	Convenient and efficient syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y