Iodine-mediated intramolecular dehydrogenative coupling: Synthesis of N-Alkylindolo[3,2-c]- and -[2,3-c]quinoline iodides

Volvoikar, P.S.; Tilve, S.G.

dc.contributor.author	Volvoikar, P.S.
dc.contributor.author	Tilve, S.G.
dc.date.accessioned	2015-06-03T09:35:52Z
dc.date.available	2016-06-03T09:35:52Z
dc.date.issued	2016
dc.identifier.citation	Organic Letters. 18(5); 2016; 892-895.	en_US
dc.identifier.uri	http://dx.doi.org/10.1021/acs.orglett.5b03392
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/2009
dc.description.abstract	An I2/TBHP-mediated intramolecular dehydrogenative coupling reaction is developed for the synthesis of a library of medicinally important 5,11-dialkylindolo[3,2-c]quinoline salts and 5,7-dimethylindolo[2,3-c]quinoline salts. The annulation reaction is followed by aromatization to yield tetracycles in good yield. This protocol is also demonstrated for the synthesis of the naturally occurring isocryptolepine in salt form.
dc.publisher	American Chemical Society	en_US
dc.subject	Chemistry	en_US
dc.title	Iodine-mediated intramolecular dehydrogenative coupling: Synthesis of N-Alkylindolo[3,2-c]- and -[2,3-c]quinoline iodides	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y