Convenient synthesis of 2, 2-dimethyl-3, 4-dihydro-2H-parano [2,3- b]quinolines

Parsekar, S.B.; Amonkar, C.P.; Parameswaran, P.S.; Tilve, S.G.

dc.contributor.author	Parsekar, S.B.
dc.contributor.author	Amonkar, C.P.
dc.contributor.author	Parameswaran, P.S.
dc.contributor.author	Tilve, S.G.
dc.date.accessioned	2015-06-04T02:36:22Z
dc.date.available	2015-06-04T02:36:22Z
dc.date.issued	2010
dc.identifier.citation	Synthetic Communications. 40(21); 2010; 3251-3258.	en_US
dc.identifier.uri	http://dx.doi.org/10.1080/00397910903398668
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/2414
dc.description.abstract	A convenient general synthesis of 2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]quinolines using the Wittig reaction is described.The o-nitrobenzaldehydes (1a-d) on reaction with phosphorane 2 provided (E)-ethyl-alpha-(2,2-dimethylprop-2-ene)-2-nitrocinnamates (3a-d) in excellent yields, which on cyclization with polyphosphoric acid followed by reductive cyclization using Fe/HCl afforded dihydropyranoquinolines (5a-d). Alternatively, the pyranoquinolines 5a-d were also synthesised from esters 3a-d by employing domino reductive cyclization in a single step.	en_US
dc.publisher	Taylor and Francis	en_US
dc.subject	Chemistry	en_US
dc.title	Convenient synthesis of 2, 2-dimethyl-3, 4-dihydro-2H-parano [2,3- b]quinolines	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y