A concise diastereoselective approach to (+)-dexoxadrol, (-)-epidexoxadrol, (-)-conhydrine and (+)-lentiginosine from (-)-pipecolinic acid

Bhat, C.; Tilve, S.G.

dc.contributor.author	Bhat, C.
dc.contributor.author	Tilve, S.G.
dc.date.accessioned	2015-06-04T03:40:31Z
dc.date.available	2015-06-04T03:40:31Z
dc.date.issued	2013
dc.identifier.citation	Tetrahedron. 69(51); 2013; 10876-10883.	en_US
dc.identifier.uri	http://dx.doi.org/10.1016/j.tet.2013.10.082
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/2866
dc.description.abstract	A new diastereoselective pathway for the total synthesis of (+)-dexoxadrol, first asymmetric synthesis of (-)-epi-dexoxadrol and formal synthesis of conhydrine and (+)-lentiginosine is presented using commercially available (-)-pipecolinic acid. The key reactions utilized are Sharpless asymmetric dihydroxylation and Wittig reaction. The paper further describes the study of effect of protecting groups on dihydroxylation of a terminal olefin in piperidine ring system.	en_US
dc.publisher	Elsevier	en_US
dc.subject	Chemistry	en_US
dc.title	A concise diastereoselective approach to (+)-dexoxadrol, (-)-epidexoxadrol, (-)-conhydrine and (+)-lentiginosine from (-)-pipecolinic acid	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y