Conhydrine: An account of isolation, biological perspectives and synthesis

Bhat, C.; Bugde, S.T.; Tilve, S.G.

dc.contributor.author	Bhat, C.
dc.contributor.author	Bugde, S.T.
dc.contributor.author	Tilve, S.G.
dc.date.accessioned	2015-06-04T04:22:26Z
dc.date.available	2015-06-04T04:22:26Z
dc.date.issued	2014
dc.identifier.citation	Synthesis-Stuttgart. 46(19); 2014; 2551-2573.	en_US
dc.identifier.uri	http://dx.doi.org/10.1055/s-0034-1379023
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/3048
dc.description.abstract	Conhydrine is a naturally occurring 2-substituted piperidine alkaloid from the plant Conium maculatum L that exists in four different forms and is known for its high toxicity. This article focuses on the synthesis of conhydrine as its medicinal applications are limited due to its high toxicity. The various asymmetric methods developed for the synthesis of conhydrine are classified based on the methodology: the chiral pool method, the chiral auixiliary method, and asymmetric catalysis. A brief overview of the complete synthetic coverage of conhydrine (1948-2014) in different isomeric forms is given.	en_US
dc.publisher	Thieme Publishing	en_US
dc.subject	Chemistry	en_US
dc.title	Conhydrine: An account of isolation, biological perspectives and synthesis	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y