Bis(indolyl)methane alkaloids: Isolation, bioactivity, and syntheses

Praveen, P.J.; Parameswaran, P.S.; Majik, M.S.

dc.contributor.author	Praveen, P.J.
dc.contributor.author	Parameswaran, P.S.
dc.contributor.author	Majik, M.S.
dc.date.accessioned	2015-09-22T08:51:04Z
dc.date.available	2015-09-22T08:51:04Z
dc.date.issued	2015
dc.identifier.citation	Synthesis. 47(13); 2015; 1827-1837.	en_US
dc.identifier.uri	http://dx.doi.org/10.1055/s-0034-1380415
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/3642
dc.description.abstract	Bis(indolyl)methane (BIM) alkaloids are an important group of bioactive natural products predominantly found in marine organisms. Thus, compounds like arsindoline A and B, vibrindole A, arundine, and trisindoline are found in marine bacteria, while the related compound, streptindole is obtained from Streptococcus faecium IB 37, found in human feces. In recent years, these molecules, which display a wide range of biological properties (antibacterial, antiviral, anti-oxidant, neurotoxic activity etc.), have attracted the attention of several synthetic and natural product chemists. This review lists selected bis(indolyl)methane analogues reported from different natural sources to date, together with their biological properties and synthesis.
dc.publisher	Thieme
dc.subject	Chemistry	en_US
dc.title	Bis(indolyl)methane alkaloids: Isolation, bioactivity, and syntheses	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y