Copper-mediated synthesis of coumestans via C(sp sup(2))-H functionalization: Protective group free route to coumestrol and 4′-O-methylcoumestrol

Naik, Mayuri M.; Kamat, V.P.; Tilve, S.G.

dc.contributor.author	Naik, Mayuri M.
dc.contributor.author	Kamat, V.P.
dc.contributor.author	Tilve, S.G.
dc.date.accessioned	2017-08-31T07:30:52Z
dc.date.available	2017-08-31T07:30:52Z
dc.date.issued	2017
dc.identifier.citation	Tetrahedron. 73(37); 2017; 5528-5536.	en_US
dc.identifier.uri	https://doi.org/10.1016/j.tet.2017.07.057
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/4893
dc.description.abstract	A simple and efficient two step synthesis of coumestans is described. The key reaction in the synthesis is the use of easily available Cu(OAc)sub(2) for C-H functionalization of 3-(2-hydroxyphenyl)coumarin to give coumestan ring system via formal oxidative cyclization. This approach provided a short protective group free route to naturally occurring coumestrol and 4′-O-methylcoumestrol.	en_US
dc.publisher	Elsevier	en_US
dc.subject	Chemistry	en_US
dc.title	Copper-mediated synthesis of coumestans via C(sp sup(2))-H functionalization: Protective group free route to coumestrol and 4′-O-methylcoumestrol	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y