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Solventless mechanosynthesis of Bis(Indolyl)Methanes

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dc.contributor.author Mhaldar, S.N.
dc.contributor.author Mandrekar, K.S.
dc.contributor.author Gawde, M.K.
dc.contributor.author Shet, R.V.
dc.contributor.author Tilve, S.G.
dc.date.accessioned 2019-02-14T04:27:39Z
dc.date.available 2019-02-14T04:27:39Z
dc.date.issued 2019
dc.identifier.citation Synthetic Communications. 49(1); 2019; 94-101. en_US
dc.identifier.uri https://doi.org/10.1080/00397911.2018.1542732
dc.identifier.uri http://irgu.unigoa.ac.in/drs/handle/unigoa/5590
dc.description.abstract Ball-milling technique as a solvent-free and an alternative green process was investigated for the eco-benign synthesis of bis(indolyl)methanes (BIMs) from various aldehydes and selected ketones with indoles in high yields. The present methodology has several advantages such as simple procedure, good yields, mild conditions, and reduced environmental consequences. The silica gel acts both as a grinding medium and an acid catalyst. The utility of this technique was demonstrated by synthesizing library of 17 BIMs including two natural products trisindoline and tris(1H-indol-3-yl)methane. en_US
dc.publisher Taylor & Francis en_US
dc.subject Chemistry en_US
dc.title Solventless mechanosynthesis of Bis(Indolyl)Methanes en_US
dc.type Journal article en_US
dc.identifier.impf y


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