Browsing Chemical Sciences by Author "Holla, H."

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Isolation, structure elucidation and in vitro anticancer activity of phytochemical constituents of Goniothalamus wynaadensis Bedd. and identification of Alpha -Tubulin as a putative molecular target by in Silico study

Sharma, A.; Talimarada, D.; Dhuri, S.N.; Sundaram, V.N.; Palanimutu, D.; Holla, H. (Chemistry & Biodiversity. 20(9); 2023; ArticleID_e202300371.)

The phytochemical analysis of ethyl acetate and methanol extract of Goniothalamus wynaadensis Bedd. leaves led to an isolation of eight (1-8) known molecules, among them seven (2-8) isolated for the first time from this ...
Synthesis, DFT analysis and in-vitro anti-cancer study of novel fused bicyclic pyranone isoxazoline derivatives of Goniodiol-diacetate-a natural product derivative

Talimarada, D.; Sharma, A.; Wakhradkar, M.G.; Dhuri, S.N.; Gunturu, K.C.; Sundaram, V.N.; Holla, H. (Fitoterapia. 163; 2022; ArticleID_105316.)

Natural products, natural product-inspired molecules and natural product derivatives have contributed around 79 percent to the new chemotherapies against the most complex, deadly disease, cancer. In this study, a series ...

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