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Total synthesis of 2-(2-Ketoalkyl)-piperidine alkaloids (+)- pelletierine, (+)-haloxynine and (-)-N-methyl-pelletierine via regioselective Wacker oxidation

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dc.contributor.author Mhaldar, S.N.
dc.contributor.author Tilve, S.G.
dc.date.accessioned 2019-08-13T09:19:53Z
dc.date.available 2019-08-13T09:19:53Z
dc.date.issued 2019
dc.identifier.citation ChemistrySelect. 4(29); 2019; 8564-8567. en_US
dc.identifier.uri https://doi.org/10.1002/slct.201902115
dc.identifier.uri http://irgu.unigoa.ac.in/drs/handle/unigoa/5816
dc.description.abstract A practical synthesis of naturally occurring piperidine alkaloids (+)-pelletierine, (+)-haloxynine and (-)-N-methyl-pelletierine is described from (-)-pipecolinic acid using Wittig reaction and Wacker oxidation as the key steps. The protocol exploits the regioselective oxidation of the internal olefins. en_US
dc.publisher Wiley en_US
dc.subject Chemistry en_US
dc.title Total synthesis of 2-(2-Ketoalkyl)-piperidine alkaloids (+)- pelletierine, (+)-haloxynine and (-)-N-methyl-pelletierine via regioselective Wacker oxidation en_US
dc.type Journal article en_US
dc.identifier.impf y


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