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A single-step synthesis of ayapin, limmettin, scoparone, leptodactylone, fraxinol, isoscopoletin, 5,6,7-trimethoxy coumarin and 7-methoxy-8-hy-droxy coumarin

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dc.contributor.author Paknikar, S.K.
dc.contributor.author Bhattacharjee, J.
dc.contributor.author Nadkarni, K.K.
dc.date.accessioned 2015-06-03T06:40:15Z
dc.date.available 2015-06-03T06:40:15Z
dc.date.issued 1994
dc.identifier.citation Journal of the Indian Institute of Science. 74(2); 1994; 277-285. en_US
dc.identifier.uri http://journal.iisc.ernet.in/archives/archives/v9-79/Vol.74(1-6)1994/Vol.74(2)1994/vol74(2)1994.pdf
dc.identifier.uri http://irgu.unigoa.ac.in/drs/handle/unigoa/659
dc.description.abstract A single-step synthesis of eight natural coumarins, namely, ayapin, limmetin, scoparone, leptodactylone, fraxinol, isoscopoletin, 5,6,7-trimethoxy coumarin and 7-methoxy-8-hydroxy coumarin is hang reported. The method involves the transfer of C-3 umt of cinnamic acids on to appropriate phenols in the presence of polyphosphorice acid (PPA) to obtain the corresponding coumanns. The ease with which the reaction occurs, the moderately good yields and the ready availability of starring materials are hallmarks of this reaction. The scope of the reaction has heen discussed in the present paper.
dc.subject Chemistry en_US
dc.title A single-step synthesis of ayapin, limmettin, scoparone, leptodactylone, fraxinol, isoscopoletin, 5,6,7-trimethoxy coumarin and 7-methoxy-8-hy-droxy coumarin en_US
dc.type Journal article en_US
dc.identifier.impf y


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