Molecular phosphonic acid-tethered tetraphenylethene AIEgen based highly selective fluorescent turn-on sensor for neomycin

Malegaonkar, J.N.; Kobaisi, M.A.; More, K.S.; Bhosale, Sidhanath V.; Bhosale, S.V.

dc.contributor.author	Malegaonkar, J.N.
dc.contributor.author	Kobaisi, M.A.
dc.contributor.author	More, K.S.
dc.contributor.author	Bhosale, Sidhanath V.
dc.contributor.author	Bhosale, S.V.
dc.date.accessioned	2023-03-28T07:07:39Z
dc.date.available	2023-03-28T07:07:39Z
dc.date.issued	2022
dc.identifier.citation	Dyes and Pigments. 198; 2022; ArticleID_110042.	en_US
dc.identifier.uri	https://doi.org/10.1016/j.dyepig.2021.110042
dc.identifier.uri	http://irgu.unigoa.ac.in/drs/handle/unigoa/6993
dc.description.abstract	We demonstrated highly selective and sensitive tetraphenylethene -tetraphosphonic acids for the facile detection of aminoglycoside antibiotic neomycin for the first time. Neomycin was found to effectively induce aggregate formation of (4-(1,2,2-tris(4-phosphonophenyl)vinyl)phenyl)phosphonic acid octasodium salt (TPPE) in aqueous solution. The aggregation-induced emission (AIE) response of TPPE was realized upon addition of neomycin in Milli-Q water at pH 7. The detection mechanism relies on electrostatic and hydrogen bonding interactions. The TPPE-based sensor system exhibited a detection limit 2.088 x 10 sup(-10) M of neomycin. Further, we demonstrate use of TPPE system for visual detection of neomycin as thin layer chromatography (TLC) sensor to develop kits for real world applications.	en_US
dc.publisher	Elsevier	en_US
dc.subject	Chemistry	en_US
dc.title	Molecular phosphonic acid-tethered tetraphenylethene AIEgen based highly selective fluorescent turn-on sensor for neomycin	en_US
dc.type	Journal article	en_US
dc.identifier.impf	y