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Domino primary alcohol oxidation-Wittig reaction: Total synthesis of ABT-418 and (E)-4-oxonon-2-enoic acid

Domino primary alcohol oxidation-Wittig reaction: Total synthesis of ABT-418 and (E)-4-oxonon-2-enoic acid

Shet, J.B.; Desai, V.G.; Tilve, S.G.
Source : Synthesis-Stuttgart. (11); 2004; 1859-1863.
URI: http://dx.doi.org/10.1055/s-2004-829123
http://irgu.unigoa.ac.in/drs/handle/unigoa/1604
Date: 2004
Document Type: Journal article

Abstract:

Domino oxidation of primary alcohols to alpha,beta-unsaturated compounds using the combination of PCC-NaOAc and stabilized Wittig reagent and its application towards total synthesis of ABT-418 and 4-oxonon-2-enoic acid is described.

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