A concise synthesis of 1-oxygenated carbazole alkaloids, Clausine E and Clausine F

Kamat, D.P.; Parsekar, S.B.; Kamat, V.P.; Tilve, S.G.

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A concise synthesis of 1-oxygenated carbazole alkaloids, Clausine E and Clausine F

Kamat, D.P.; Parsekar, S.B.; Kamat, V.P.; Tilve, S.G.

Source : Synthesis. 46(20); 2014; 2789-2793.

URI: http://dx.doi.org/10.1055/s-0034-1378521
http://irgu.unigoa.ac.in/drs/handle/unigoa/1724

Date: 2014

Document Type: Journal article

Abstract:

A rapid entry into naturally occurring and biologically important 1-oxygenated carbazole clausine E was established through Wittig reaction and annulation. Further O-prenylation of clausine E by Mitsunobu reaction followed by p-Claisen rearrangement delivered clausine F.

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