Double reductive cyclization: A facile synthesis of the indoloquinoline alkaloid cryptotackieine

Parvatkar, P.T.; Parameswaran, P.S.; Tilve, S.G.

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Double reductive cyclization: A facile synthesis of the indoloquinoline alkaloid cryptotackieine

Parvatkar, P.T.; Parameswaran, P.S.; Tilve, S.G.

Source : Tetrahedron Letters. 48(44); 2007; 7870-7872.

URI: http://dx.doi.org/10.1016/j.tetlet.2007.08.126
http://irgu.unigoa.ac.in/drs/handle/unigoa/1978

Date: 2007

Document Type: Journal article

Abstract:

A new synthesis of the indoloquinoline alkaloid cryptotackieine, isolated from Cryptolepis sanguinolenta, is described which involves a Perkin reaction, a tandem double reduction-double cyclization reaction followed by regioselective methylation at the quinoline nitrogen.

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