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Synthesis of (-)-hygrine, (-)-norhygrine, (-)-pseudohygroline and (-)-hygroline via Nef reaction

Synthesis of (-)-hygrine, (-)-norhygrine, (-)-pseudohygroline and (-)-hygroline via Nef reaction

Bhat, C.; Tilve, S.G.
Source : Tetrahedron Letters. 52(49); 2011; 6566-6568.
URI: http://dx.doi.org/10.1016/j.tetlet.2011.09.118
http://irgu.unigoa.ac.in/drs/handle/unigoa/2546
Date: 2011
Document Type: Journal article

Abstract:

Synthesis of tropane alkaloids (-)-hygrine, (-)-norhygrine and sedum alkaloids (-)-pseudohygroline and (-)-hygroline is described from L-proline via Henry and Nef reactions.

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