Biogenetic-type synthesis of 2-hydroxy-4,4,7-trimethyl-1(4h)-naphthalenone, a modified apocarotenoid from Ipomoea pes-caprae

Fondekar, K.P.P.; Paknikar, S.K.; Torres, S.; Kamat, S.P.

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Biogenetic-type synthesis of 2-hydroxy-4,4,7-trimethyl-1(4h)-naphthalenone, a modified apocarotenoid from Ipomoea pes-caprae

Fondekar, K.P.P.; Paknikar, S.K.; Torres, S.; Kamat, S.P.

Source : Natural Product Communications. 7(7); 2012; 827-830.

URI: http://irgu.unigoa.ac.in/drs/handle/unigoa/2706

Date: 2012

Document Type: Journal article

Abstract:

A biogenetic-type synthesis of 2-hydroxy-4,4,7-trimethyl-1(4H)-naphthalenone (1), a modified apocarotenoid isolated from Ipomoea pes-caprae (Linn.) R.Br. showing anti-inflammatory activity by inhibiting prostaglandin synthesis in vitro, is described. A biogenetic proposal for the natural occurrence of 1 is also presented.

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