Transport of alpha-santonin via 2 independent pathways by pseudomonas strain-s ATCC-43388

Colaco, D.; Furtado, I.; Naik, U.P.; Mavinkurve, S.; Paknikar, S.K.

Transport of alpha-santonin via 2 independent pathways by pseudomonas strain-s ATCC-43388

Colaco, D.; Furtado, I.; Naik, U.P.; Mavinkurve, S.; Paknikar, S.K.

Source : Letters in Applied Microbiology. 17(5); 1993; 212-214.

URI: http://dx.doi.org/10.1111/j.1472-765X.1993.tb01449.x
http://irgu.unigoa.ac.in/drs/handle/unigoa/525

Date: 1993

Document Type: Journal article

Abstract:

Pseudomonas strain S (ATCC 43388) transforms alpha-santonin in the presence of dicyclohexylcarbodiimide (DCCD) to 1,2-dihydrosantonin (DHS) and two more products, D1 and D2. D2 was identified as 4,5-dihydroxysantonin (DHXS). Cells incubated with semicarbazide (SC) formed DHXS but not DHS. Simultaneous formation of DHS and DHXS is indicative of the presence of two distinct pathways of alpha-santonin biotransformation.

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