Domino Bischler-Napieralski - Michael reaction and oxidation, a new route to Coumarin-Pyrrole-Isoquinoline fused pentacycles

Mandrekar, K.S.; Kadam, H.K.; Tilve, S.G.

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Domino Bischler-Napieralski - Michael reaction and oxidation, a new route to Coumarin-Pyrrole-Isoquinoline fused pentacycles

Mandrekar, K.S.; Kadam, H.K.; Tilve, S.G.

Source : European Journal of Organic Chemistry. 47; 2018; 6665-6670.

URI: https://doi.org/10.1002/ejoc.201801244
http://irgu.unigoa.ac.in/drs/handle/unigoa/5548

Date: 2018

Document Type: Journal article

Abstract:

Lamellarin scaffold is synthesized by a metal free convergent route involving domino Bischler-Napieralski reaction - Michael reaction - oxidation sequence. Six lamellarin analogues were synthesised having substituent on aryl as well as coumarin ring A.

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