Abstract:
Carbon nanomaterials have been applied in various fields. Currently, functionalized carbon nanomaterial with practical tuning and surface functionalization is a tremendously used method. Herein, neomycin-based fluorescent carbon quantum dots were synthesized via hydrothermal method using neomycin and citric acid as a source for selective sensing of Fe sup(3+) metal ions. The as-prepared Neo-CA-CQDs exhibited blue fluorescence, successfully characterized and utilized for sensing various metal ions. The carbon dots showed excellent sensing properties towards Fe sup(3+) metal ions and optical properties were characterized by a fluorescence spectrofluorometer. In addition, pH and biocompatibility studies were investigated for the Neo-CA-CQDs. The average size of the Neo-CA-CQDs was 3-5.7 nm. The quantum yield of the as-prepared Neo-CA-CQDs was 29.3 percent. The limit of detection for Fe sup(3+) sensing was determined to be 6.09 mu M. The sensing of Fe sup(3+) ions was also confirmed through visual detection, as a significant color change of the CQDs was observed. Additionally, a competitive study was conducted to verify the selectivity of the neomycin citric acid-mediated CQDs towards Fe sup(3+). The in vitro cytotoxicity study was performed on a mouse fibroblast cell line (L929) and Human cervical cancer cell line (HeLa).
