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Synthesis of flavans: One-pot synthesis of flavans from 4-methylcoumarins

Synthesis of flavans: One-pot synthesis of flavans from 4-methylcoumarins

Kamat, V.P.; Asolkar, R.N.; Kirtany, J.K.
Source : Synthetic Communications. 28(24); 1998; 4581-4587.
URI: http://dx.doi.org/10.1080/00397919808004523
http://irgu.unigoa.ac.in/drs/handle/unigoa/974
Date: 1998
Document Type: Journal article

Abstract:

4-Methylcoumarins (2), obtained by condensation of suitable phenols (1) with ethyl acetoacetate in the presence of sulfuric acid, lead directly to flavans (3) when refluxed with sodium hydroxide and ethanediol.

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